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Silent contributors to injury - illness - performance, 18-19 March 2016 : Session 2 - Pathology : Molecular mechanisms causing common exercise-associated musculoskeletal soft tissue injuries / Malcolm Collins.

Catalogue Information
Field name Details
Record Number 512936
Item Type Video
E Resource
Meeting Name Sports medicine Australia. Conference (2016 : Canberra, ACT.)
Title Silent contributors to injury - illness - performance, 18-19 March 2016 : Session 2 - Pathology : Molecular mechanisms causing common exercise-associated musculoskeletal soft tissue injuries / Malcolm Collins.
Published 2016
Description 1 streaming video (approximately 56 minutes) : mp4 file + 1 computer file (PDF)
Content Type two-dimensional moving image
Media Type computer
Carrier Type online resource
Series 2016 Conferences
Notes Available for Clearinghouse for Sport member groups B, C, D & E only.
Contents Conference program session 2 - Pathology : Changes in muscle morphology, neuromuscular capacity and tendon function with training: implications for athletic performance, patient rehabilitation and aging individuals / Professor Per Aagaard, University of Southern Denmark -- When the neuroimmune system screams: Practical Applications of DIMs and SIMs / Associate Professor David Butler, Neuro Orthopaedic Institute and University of South Australia -- Molecular mechanisms causing common exercise-associated musculoskeletal soft tissue injuries / Professor Malcolm Collins, University of Cape Town -- Role of collagen to keep tendon structures strong and healthy / Dr Stephan Praet, Australian Institute of Sport -- •Questions and answers session / Pathology panel.
Presenter Presenter : Malcolm Collins is currently a Professor and head of the Department of Human Biology at the University of Cape Town (UCT). He obtained a BSc degree majoring in Biochemistry and Human Physiology from Stellenbosch University in South Africa. In 1988 in received a BSc (Hons) degree Cum Laude in Biochemistry, also from Stellenbosch University, followed by a PhD in Medical Biochemistry on collagen gene expression from the UCT in 1993. After completing Post-Doctoral work also in extracellular matrix protein gene expression at the University of Washington in Seattle, USA, he joined UCT’s and the South African Medical Research Council’s Research Unit for Exercise Science and Sports Medicine in Cape Town. Prof Collins’ doctoral and post-doctoral work in extracellular matrix biology, in particular collagen, gene expression, stimulated his current research focus on elucidating the molecular mechanisms causing common exercise-associated musculoskeletal soft tissue (tendons, ligaments and skeletal muscle) injuries. He has developed a very productive research team at UCT, which has published a number of seminal papers on the identification of genetic risk associated factors for common tendon and ligament injuries. This UCT-based research group is currently internationally recognized as the pioneers and authority in this area of research. As a result he has developed an international and national, interdisciplinary network of research collaborators, consisting of clinicians and scientists. He has supervised or is currently supervising, several post-doctoral fellows and nearly 40 masters and doctoral students. He has also published more than 100 peer-reviewed papers, review articles and book chapters. He is a Fellow of the European College of Sport Science and is a member of the editorial teams of several international scientific journals, including the British Journal of Sports Medicine.
Summary This Symposium was jointly presented by Sports Medicine Australia ACT and the Australian Institute of Sport. Sub themes for the conference include: Planning Periodisation – Training errors, planning for performance, monitoring injury/illness/performance, planning for the gaps and travel ; Pathology Specific – Muscle, tendon, pain, mental health, gender ; Medical – Iron, Viral, respiratory, infectious diseases, vitamins, probiotic, immunology, genetic development ; Physical – sleep, body composition, energy availability, making weight, gender.
Abstract : Evidence from familial and genetic association studies have reported that DNA sequence variants play an important role, together with non-genetic factors, in the aetiology of common musculoskeletal soft tissue injuries. The associated variants, which have been identified to date, may contribute to the inter-individual variation in the structure and, by implication, mechanical properties of the collagen fibril and surrounding matrix within musculoskeletal soft tissues, as well as their response to mechanical loading and other stimuli. Our present knowledge of the influence of genetic patterns on these injuries will be reviewed, with a focus on the possible biological mechanisms by which genetic factors are involved in the aetiology of musculoskeletal soft tissue injuries. The establishment of multidisciplinary international consortia for the identification of biologically relevant injury associated variants using whole-genome screening techniques, will also be reviewed. Finally, although clinicians and coaches need to be made aware that many direct-to-consumer companies are prematurely marketing genetic tests directly to athletes, current practice can nevertheless consider susceptibility for specific musculoskeletal injuries. Potential susceptible athletes may then be individually managed to reduce their risk profile.
Subjects Conference
Sports medicine
Soft Tissue Injuries
musculoskeletal system
Added Author Collins, Malcolm, Professor University of Cape Town, South Africa.
Added Corporate Name Australian Institute of Sport
Electronic Resource Click here to watch streaming video (this video is only available to member groups B, C, D and E)
2016 Conference schedule (PDF)
Clearinghouse for Sport Client Services Model (access restrictions explained)
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